Calithera is an innovative biopharmaceutical company in the clinical stage, leading the exploration and advancement of targeted, small molecule treatments that disturb cellular metabolic pathways to selectively hinder tumor cell growth and improve immune-cell function. Tumor metabolism and tumor immunology present promising interconnected domains for the discovery of cancer medications, providing the potential for entirely new therapies for individuals battling cancer and other life-threatening ailments. The Calithera pipeline comprises several original compounds that aim at crucial metabolic enzymes to disrupt metabolic pathways crucial for tumor and other diseased cells.