The BioPharma Crescent, located to the East of the RTP, encompasses a five County region and is recognized as one of the largest hubs for biopharma manufacturing on the East Coast. Leading companies such as Novo Nordisk, Merck, Pfizer, and Thermo Fisher Scientific have established important facilities within the Crescent. The biopharma industry in this region employs nearly 10,000 individuals and contributes to a $3 billion economic activity.